Name: Doctor's Formulas D-Mannose 30caps
Brand: Doctor's Formulas
SKU: DB_31313
Availability: OutOfStock

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Doctor's Formulas D-Mannose 30caps

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Unavailable 8.73€

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Barcode: 5200403400888

Product code: 31313

Brand: Doctor's Formulas

Brand categories: Doctor's Formulas Urinary System , Doctor's Formulas Uroloimwxh

Categories: Urinary System , Uroloimwxh

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The D - Mannose formula is a dietary supplement containing the monosaccharide D-mannose.

What is D-Mannose?

D-mannose is a simple sugar that has a special contribution to metabolism, through its role in the glycosylation of certain proteins. D-mannose is rapidly absorbed and reaches peripheral organs in about 30 minutes and is then excreted by the urinary system. It cannot be converted into glycogen, therefore, it is not stored in the body. It attaches to lectins and thus prevents the attachment of pathogenic organisms to the walls of the bladder.

Mechanism of Action

Its mechanism of action is expressed through the inhibition of the adhesion of the FimH surface protein. By directly binding FimH to D-mannose that is attached to a carrier protein, which is responsible for receptor specialization.

The first adhesion stage involves the mannose-sensitive adhesion of FimH to the epithelium. The wall of the bladder is covered with various mannose-glycosylated proteins, such as the Tamm-Horsfall protein (THP) that directly interferes with the adhesion of microbes to the mucosa. The Tamm-Horsfall protein (THP) can bind to E. Coli with a specific bond, which can be inhibited by exogenous D-mannose.

By inhibiting the adhesion of microbes to the urinary tract epithelium, D-mannose mimics the function of the urinary tract epithelial barrier.

Doctor's Formulas D-Mannose 30caps

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