Liposomes belong to the colloidal dispersions of bioactive molecule transport systems which have the ability to transport them, improving their effectiveness. The dimensions of liposomes according to their preparation method and the physical and chemical characteristics of their structural units are in the order of nanometers up to a few micrometers.
Historically, in the early 1960s, there was a tendency to study the biophysical properties of colloidal systems that had a lipid and phospholipid composition, with the aim of understanding the biophysical functions of cells. The biophysicist A.D. Bangham studied lipid colloidal dispersions to simulate cell membranes and study their functionality.
Liposomes, if prepared from structural materials like those of our cells, have advantages related to their 'friendliness' to human tissues. They have the ability to transport lipophilic bioactive molecules that do not easily dissolve in aqueous media and thus have problems with absorption and bioavailability, e.g., vitamins, curcumin, etc., as well as water-soluble or amphiphilic molecules, improving their dissolution rate and absorption through the gastrointestinal tract.
Liposomes can also transport bioactive substances and improve their passage through the barriers of the gastrointestinal tract and are effective'vehicles' for transporting bioactive molecules.
Liposomal technology and especially the innovative technology of supramolecular phospholipid complexes with a structure of lipid bilayers can improve the therapeutic effectiveness of dietary supplements and are an innovation in this field, providing high added value to the final dosage form.
This text was created in collaboration with the Laboratory of Pharmaceutical Nanotechnology of the Department of Pharmacy of the National and Kapodistrian University of Athens
Bibliography: (1) K. Demetzos. 'Pharmaceutical Nanotechnology. Basic Principles and Practical Applications', Ed. Parisianos, 2014 (2) Y. Perrie, T. Rades 'Pharmaceutical Technology-Transport and Targeted Action of Drugs', Scientific Editor K. Demetzos, Ed. Parisianos, 2016.
R-ALPHA LIPOIC ACID is a dietary supplement containing R-alpha lipoic acid. The liposomal formulation technology results in greater absorption and bioavailability of the active ingredients of the preparation.
WARNINGS: - Do not exceed the recommended daily dose. - SDs should not be used as a substitute for a balanced diet. - Keep out of reach of children. - This product is not intended for the prevention, treatment, or cure of human disease. - Consult your doctor if you are pregnant, breastfeeding, under medication, or have health problems
E.O.P. Notification Number: 48976/14.6.2016 (The Notification Number with the E.O.P. does not imply a marketing authorization from the E.O.P.)
